Both animal and clinical studies have demonstrated that omega-3 fatty acids have anti-arrhythmic properties. It has been suggested that these anti-arrhythmic effects are due to modulation of the activity of various myocardial calcium handling proteins such as ryanodine receptor (RyR), L-type calcium current and sodium/calcium exchanger. In this article, we review all the data available on the effects of omega-3 fatty acids on ventricular myocardial calcium handling. In addition we highlight some unanswered questions and discuss possible therapeutic benefits of omega-3 fatty acids. © 2012 Sankaranarayanan and Venetucci.
CITATION STYLE
Sankaranarayanan, R., & Venetucci, L. (2012). Are the anti-arrhythmic effects of omega-3 fatty acids due to modulation of myocardial calcium handling. Frontiers in Physiology, 3 OCT. https://doi.org/10.3389/fphys.2012.00373
Mendeley helps you to discover research relevant for your work.