A genome-wide association study for morphometric traits was conducted in 184 Quarter Horses, 120 from a racing population, and 64 from a cutting population, which were genotyped using the Illumina EquineSNP50 chip. Association analysis was performed with 42,058 single-nucleotide polymorphisms (SNPs) (after quality control) using Qxpak5 software. Thefollowing traits were measured: weight (W), rump length (RL), and body length (BL). These morphometric traits are important for the best performance in race and cutting events. Forweight, three SNPs associated (P < .0001) were found on chromosomes (Equus caballus autosomes [ECA]) 2 and 3. For rump length, eight SNPs associated (P < .0001) were found on ECA 2, 3, 6, 7, 9, 21, and 26. On ECA 3 and ECA 8, two SNPs were associated (P < .0001) with body length. So, a total of 13 important chromosomal regions were identified with Qvalues of 0.53 (SNPs for W), 0.40 (SNPs for RL), and 0.99 (SNPs for BL). Positional and functional candidate genes emerging from this study were WWOX and AAVPR1A. Further studies are required to confirm these associations in other populations. © 2014 Elsevier Inc.
CITATION STYLE
Meira, C. T., Farah, M. M., Fortes, M. R. S., Moore, S. S., Pereira, G. L., Silva, J. A. I. V., … Curi, R. A. (2014). A genome-wide association study for morphometric traits in quarter horse. Journal of Equine Veterinary Science, 34(8), 1028–1031. https://doi.org/10.1016/j.jevs.2014.05.011
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