Studies on changes in hematological and biochemical parameters in smokeless tobacco (Gutka) chewing auto drivers in Nellore district of Andhra Pradesh, India

Abstract

The present study was designed to evaluate the effect of Smokeless tobacco on some biochemical and haematological parameters. It was observed that hematological parameters of Autodrivers including hemoglobin content, white blood cell and leukocyte counts were higher in Gutka consumers than in controls, where as monocytes and basophils counts were lower. Higher biochemical parameters like serum cholesterol, glucose and protein were observed in blood samples of Gutka consumers. Decrease in serum protein levels and remarkable increase in Serum cholesterol and glucose levels were observed in Gutka consumers when compared to controls. There existed considerable difference among different hematological and biochemical parameters of gutka chewers when compared to controls.