Smoking Effects on Blood Antioxidants Level: Lactate Dehydrogenase, Catalase, Superoxide Dismutase and Glutathione Peroxidase in University Students

Abstract

Smoking has been involved as a significant risk factor for series and establishment of diseases. The aim of our study to investigate smoking effects induced oxidative damage. We have chosen male students of Al-Iraqia University and Tikrit University, aged 20-23 years. In our study we measured activity of Lactate Dehydrogenase (LDH), Catalase (CAT), Superoxide Dismutase (SOD), and Glutathione Peroxidase (GXp). Our results showing that the level of LDH in smokers were higher than nonsmokers, and the levels of CAT was higher in group of nonsmokers ,while SOD and GXp were higher significantly in non-smokers when comparison with smoker students. Also we study the height, body weight, body mass index (BMI), and some of blood parameters red blood cells (RBCs), White blood cells (WBCs), and hemoglobin (Hb). Results showing significant differences between smokers and nonsmokers, all of these parameters were lower in smokers. These results perhaps indicate that smoker students have oxidative stress and shortness in antioxidants defense system.