The DNA denaturation, the double-stranded DNA unwinding process, is a vital process for cells. The percentage of the denaturation is used as an index of organism complexity and it is the base of the DNA hybridisation technique, which provides a great deal of information. It can be detected by observing the increase in the ability of a DNA solution to absorb ultraviolet light at a wavelength of 260 nm. Based on experimental data, we found a mathematical model capable of predicting the behaviour of a general DNA, given the melting temperature Tm.
CITATION STYLE
Guarguagli, S., & Pastrone, F. (2018). A mathematical model of nucleic acid thermodynamics. In Advanced Structured Materials (Vol. 89, pp. 387–394). Springer Verlag. https://doi.org/10.1007/978-3-319-72440-9_20
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