Efficacy of bromochlorodimethylhydantoin against Legionella pneumophila in industrial cooling water

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Abstract

Free residual chlorine and bromine can be generated in water from bromochlorodimethylhydantoin (BCDMH). Efficacy of chlorine from inorganic sources has been studied extensively, but there is much less information on the efficacy of bromine against L. pneumophila; only a few efficacy studies of organically-derived. halogen appear in the literature and the results from different studies conflict or are difficult to interpret. This paper describes the efficacy of halogen from BCDMH against planktonic, pure culture L. pneumophila in an industrial cooling water. There was no difference in efficacy between halogen derived from organic or inorganic sources in controlled laboratory experiments. Effective doses in laboratory studies cannot be translated directly to field applications because of significant differences in the microbiology. However, the data suggest that disinfection (>99.9% reduction in viability within 10 min) of planktonic, pure culture L. pneumophila can be achieved with about 1 ppm free residual halogen (expressed as chlorine) from BCDMH in a typical industrial cooling water. © 1989 Society for Industrial Microbiology.

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McCoy, W. F., & Wireman, J. W. (1989). Efficacy of bromochlorodimethylhydantoin against Legionella pneumophila in industrial cooling water. Journal of Industrial Microbiology, 4(6), 403–408. https://doi.org/10.1007/BF01569635

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