Cord blood T cells are "completely different"

Abstract

According to some, one of Britain's significant contributions to the modern world is the comedy of the Monty Python Flying Circus. One of their films employed the memorable catchphrase, "And now for something completely different... ." Now, decades later, in this issue of Blood, the work of Hiwarkar et al represents another notable English export.1 This group of investigators has begun to dissect the differences in graft-versus-tumor effects of adult donor peripheral blood (PB) and cord blood (CB) T cells, and the findings are quite remarkable.