Many protein regions and some entire proteins have no definite tertiary structure, presenting instead as dynamic, disorder ensembles under different physiochemical circumstances. These proteins and regions are known as Intrinsically Unstructured Proteins (IUP). IUP have been associated with a wide range of protein functions, along with roles in diseases characterized by protein misfolding and aggregation.
CITATION STYLE
Yang, J. Y., & Yang, M. (2008). Predicting protein disorder by analyzing amino acid sequence. BMC Genomics, 9(Suppl 2), S8. https://doi.org/10.1186/1471-2164-9-s2-s8
Mendeley helps you to discover research relevant for your work.