Interactomics: Interactions and Regulatory Networks

Abstract

This chapter deals with networks of various kinds, notably the network of protein–protein interactions and regulatory networks. The biophysicochemical aspects of the interactions, including specificity and cooperative binding, are discussed, followed by an account of the various in vivo and in vitro (including chromatography and biosensing) experimental methods that can be used to gather the primary data on interactions, from which interactomic inferences may follow.