Device and programming abstractions for spatiotemporal control of active micro-particle swarms

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Abstract

We present a hardware setup and a set of executable commands for spatiotemporal programming and interactive control of a swarm of self-propelled microscopic agents inside a microfluidic chip. In particular, local and global spatiotemporal light stimuli are used to direct the motion of ensembles of Euglena gracilis, a unicellular phototactic organism. We develop three levels of programming abstractions (stimulus space, swarm space, and system space) to create a scripting language for directing swarms. We then implement a multi-level proof-of-concept biotic game using these commands to demonstrate their utility. These device and programming concepts will enhance our capabilities for manipulating natural and synthetic swarms, with future applications for on-chip processing, diagnostics, education, and research on collective behaviors.

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Lam, A. T., Samuel-Gama, K. G., Griffin, J., Loeun, M., Gerber, L. C., Hossain, Z., … Riedel-Kruse, I. H. (2017). Device and programming abstractions for spatiotemporal control of active micro-particle swarms. Lab on a Chip, 17(8), 1442–1451. https://doi.org/10.1039/c7lc00131b

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