Screening of Tryptophan Synthase Inhibitors as Leads of Herbicide Candidates

Abstract

We screened chemicals that inhibit tryptophan synthase for the purpose of finding the leads of herbicide candidates and found two potent inhibitors, 4-(dimethylamino)pyridine and 2-mercaptobenzimidazole; the former did not show any marked effect on rice (Oryza sativa) plants, whereas the latter showed considerable phytotoxicity to rice seedlings. © 1989, Pesticide Science Society of Japan. All rights reserved.