Seminalplasmin-an antimicrobial protein from bovine seminal plasma which acts in E.coli by specific inhibition of rRNA synthesis [17]

Abstract

SEMINAL PLASMA-The fluid in which spermatozoa are ejaculated-Has been known to inhibit reversibly both RNA and protein synthesis in sperm cells 1-3. Here we report the isolation from seminal plasma, purification to homogeneity, and characterisation of a protein which we have called 'seminalplasmin', that specifically inhibits rRNA synthesis in Escherichia coli and is highly antimicrobial. © 1979 Nature Publishing Group.