Current issues in the management of genital herpes

Abstract

Genital infection by herpes simplex virus (HSV) produces a variety of clinical manifestations, patient presentations and management problems which differ in their severity and complexity. In the UK the currently available data for the incidence of genital HSV have been provided predominantly by the KC60 returns from diagnoses made in genitourinary (GU) medicine clinics. The increasing availability and recent publication of the first results, using HSV type-specific antibody tests within GU and non-GU patient populations, provide a tool to monitor trends in the epidemiology of HSV. It is, however, important to understand that the sexual behaviour which leads to this infection is variable and not necessarily general. The clinical availability of type-specific HSV antibody tests also gives rise to the possibility of screening individuals and informing those who test positive of their, previously undiagnosed, condition. The practicalities and problems of this approach need to be fully assessed. The possibility of uncovering previously undiagnosed cases through general practitioners is being considered, first, in terms of surveys of the general practitioners' management of genital HSV and, secondly, because the funding of health care in the UK has put the cost-effectiveness in GU medicine clinics under the spotlight. This paper will explore the new developments in the management of genital HSV and suggests adherence to the clear principles of diagnosis and treatment that is in the patient's best interest. This has the clear aim of improving the patient's quality of life, a factor which must remain paramount as new technologies, health-care strategies and therapies become available.