Association of Helicobacter Pylori Infection and Diabetes Mellitus Type 2 Subjects in Yaounde Cameroon Using a Panel of Serum Biomarkers (PGII, HpIgG): A Case Control Study

Abstract

Introduction: Infection to Helicobacter pylori has been associated to many gastrointestinal diseases including gastri-tis, peptic ulcer disease, gastroesophageal reflux disease, atrophic gastritis and gastric cancer. Chronic infections are frequent and severe in patients with diabetes mellitus (DMT2), probably due to the impairment of their immune status. The link between H. pylori infection and diabetes mellitus (DM) remains controversial. This study aimed at detection and comparison of anti H. pylori antibodies (IgG) in serum of diabetes mellitus type 2 (DMT2) and non-diabetic dyspepsia subjects and also to find if there exists any significant correlation between H. pylori infection and DMT2.