Recently Chu et al. conducted a two-stage genome wide association study in Chinese that identified a novel X-linked Graves' disease (GD) susceptibility marker at rs3827440 - a nonsynonymous (P162S) nucleotide transition (519C
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Szymański, K., Miśkiewicz, P., Pirko, K., Jurecka-Lubieniecka, B., Kula, D., Hasse-Lazar, K., … Ploski, R. (2014). rs3827440, a nonsynonymous single nucleotide polymorphism within GPR174 gene in X chromosome, is associated with Graves’ disease in Polish Caucasian population. Tissue Antigens, 83(1), 41–44. https://doi.org/10.1111/tan.12259
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