Abstract
Three pharmacological agents in use as “potassium-sparing” drugs have been tested by serial measurements of total exchangeable potassium (ke) during 4 to 12 weeks of oral diuretic therapy in hypertensive subjects. Triamterene seemed ineffective in the dosage used (50 mg twice daily). Spironolactone (25 mg twice daily) reduced K loss to a considerable extent, while Slow-K (32 mEq daily) completely reversed previous ke deficits. Plasma K levels were a poor indication of degree of ke restoration. © 1971, British Medical Journal Publishing Group. All rights reserved.
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CITATION STYLE
Muldowney, F. P., Donohoe, J. F., Brien, T. G., Healy, J. J., & Canning, B. S. J. (1971). Potassium-sparing Agents during Diuretic Therapy in Hypertension. British Medical Journal, 2(5764), 739–741. https://doi.org/10.1136/bmj.2.5764.739
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