Evaluation of in-vitro immunomodulatory activity of aqueous and ethanolic extract of Capparis moonii

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Abstract

The present study was intended to evaluate the in-vitro immunomodulatory activity of aqueous and ethanolic extract of dried fruits of Capparis moonii Wight. Effect of both the extracts were evaluated at various concentrations (832 μg/ml to 6.5 μg/ml) for secretion of variouesmediators like nitric oxide, superoxide, lysosomal enzyme etc of isolated murine peritoneal macrophages. Both the extracts showed in-vitro phagocytic stimulation of, lysosomal enzyme and myeloperoxidase activity and nitric oxide in peritoneal mouse macrophages. In-vitro phagocytic index showed significant results and thus proving the need for confirmation through in-vivo studies.

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Kanase, V. G., Jain, D. B. B., & Yadavc, P. (2013). Evaluation of in-vitro immunomodulatory activity of aqueous and ethanolic extract of Capparis moonii. International Journal of Pharma and Bio Sciences, 4(2). https://doi.org/10.22159/ajpcr.2020.v13i6.36031

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