A novel role of cellular interactions in vascular calcification

Citations of this article
Mendeley users who have this article in their library.

This article is free to access.


A series of clinical trials have confirmed the correlation between vascular calcification (VC) and cardiovascular events and mortality. However, current treatments have little effects on the regression of VC. Potent and illustrative mechanisms have been proven to exist in both bone metabolism and VC, indicating that these two processes share similarities in onset and progression. Multiple osteoblast-like cells and signaling pathways are involved in the process of VC. In this review, we summarized the roles of different osteoblast-like cells and we emphasized on how they communicated and interacted with each other using different signaling pathways. Further studies are needed to uncover the underlying mechanisms and to provide novel therapies for VC.




Bardeesi, A. S. A., Gao, J., Zhang, K., Yu, S., Wei, M., Liu, P., & Huang, H. (2017, May 3). A novel role of cellular interactions in vascular calcification. Journal of Translational Medicine. BioMed Central Ltd. https://doi.org/10.1186/s12967-017-1190-z

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free