Primary amenorrhea due to empty sella: An underestimated entity

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Abstract

We report a 16-year-old girl who had stunted growth and primary amenorrhea presenting with headache and vomiting. MRI of brain showed posterior fossa dermoid cyst with hydrocephalus and empty sella. Growth hormone (GH), Leutinizing hormone (LH) and Follicular stimulating hormone (FSH) were grossly reduced on endocrinological work-up. She underwent suboccipital midline craniectomy and complete excision of dermoid cyst .She had no additional deficit after the surgery. She had menarche six months after the surgery and developed adequate secondary sexual characters, however her height remains subnormal at follow-up after 2 years as compared to age matched controls. We briefly review the radiological features, pathogenesis and outcome of this underestimated entity.

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Dange, N., Redhu, R., Kawale, J., & Mahore, A. (2012). Primary amenorrhea due to empty sella: An underestimated entity. Turkish Neurosurgery, 22(4), 499–501. https://doi.org/10.5137/1019-5149.JTN.3901-10.0

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