Bioequivalence Study of Generic Metformin Hydrochloride in Healthy Nigerian Volunteers

Abstract

Metformin is key in the management of type 2 diabetes mellitus but also represents additional financial burden, particularly with the use of branded products. The availability of generic products permits generic substitution with a much-reduced cost of treatment. However, only generic products that offer similar bioavailability with the innovator should be considered. This study was designed to assess the bioequivalence of generic metformin tablets within Nigeria.