This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.
CITATION STYLE
Kutikhin, A. G., & Yuzhalin, A. E. (2013). Genomics of pattern recognition receptors: Applications in oncology and cardiovascular diseases. Genomics of Pattern Recognition Receptors: Applications in Oncology and Cardiovascular Diseases (Vol. 9783034806886, pp. 1–185). Springer Basel. https://doi.org/10.1007/978-3-0348-0688-6
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