A new self microemulsifying mouth dissolving film

Abstract

A self micro-emulsifying mouth dissolving film (SMMDF) is a dosage form which is based on mouth dissolving film integrated with self micro emulsifying components. Stability of self-micro emulsifying drug delivery system is one of major problem of lipid based drug delivery system. This can be minimized by converting liquid self micro emulsifying drug delivery system into solid SMMDF. This drug delivery system enjoys both advantages of self micro emulsifying drug delivery system (SMEDDS) along with mouth dissolving film (MDF). Self micro-emulsifying mouth dissolving film formulations can be used to improve the oral bioavailability of hydrophobic drugs due to their efficiency of presenting the hydrophobic drug in solubilized form. This review article tries to describe the formulation of MDF and also talks about the SMEDDS. Some of the patented preparations of SMEDDS are also listed.