Construction of chiral 1,2-cycloalkanopyrrolidines from L-proline using ring closing metathesis (RCM)

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Abstract

An efficient synthetic method for the preparation of optically active pyrroloazocine, pyrroloazepine, quinolizidine, indolizidine using ring closing olefin metathesis (RCM) is described.

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APA

Arisawa, M., Takahashi, M., Takezawa, E., Yamaguchi, T., Torisawa, Y., Nishida, A., & Nakagawa, M. (2000). Construction of chiral 1,2-cycloalkanopyrrolidines from L-proline using ring closing metathesis (RCM). Chemical and Pharmaceutical Bulletin, 48(10), 1593–1596. https://doi.org/10.1248/cpb.48.1593

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