JDet: Interactive calculation and visualization of function-related conservation patterns in multiple sequence alignments and structures

Abstract

We have implemented in a single package all the features required for extracting, visualizing and manipulating fully conserved positions as well as those with a family-dependent conservation pattern in multiple sequence alignments. The program allows, among other things, to run different methods for extracting these positions, combine the results and visualize them in protein 3D structures and sequence spaces. © The Author 2011. Published by Oxford University Press. All rights reserved.