Transition metal catalysis in organic synthesis: Reflections, chirality and new vistas

Abstract

Abstract: The power of transition metal catalysis as a tool in organic synthesis is exemplified by the recent progress in the following areas: (i) diastereocontrol of Pd(0)-, Mo(0)-, and Ni(0)catalyzed allylic substitution; (ii) Pd(0)-catalyzed asymmetric allylic substitution; (iii) Hartwig-Buchwald amination; and (iv) Suzuki coupling. Development of novel, bidentate bginaphthyl ligands (MAP) and their unique mode of P.Cσ-coordination is also described. © 1999 IUPAC.