Presence of squalene in gram-positive bacteria

Abstract

The presence of the isoprenoid squalene, synthesized de novo was demonstrated in 64 out 73 strains of gram-positive bacteria by thin-layer chromatography. This observation was confirmed by gas-liquid chromatography, chemical reactivity, incorporation of radiolabeled precursor, and by gas chromatographymass spectroscopy of thin-layer chromatography-recovered material.