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Putting a New Spin of G-Quadruplex Structure and Binding by Analytical Ultracentrifugation

Humana Press Inc., (2019), 87-103
DOI: 10.1007/978-1-4939-9666-7_5
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Abstract

Analytical ultracentrifugation is a powerful biophysical tool that provides information about G-quadruplex structure, stability, and binding reactivity. This chapter provides a simplified explanation of the method, along with examples of how it can be used to characterize G4 formation and to monitor small-molecule binding.

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Dean, W. L., Gray, R. D., DeLeeuw, L., Monsen, R. C., & Chaires, J. B. (2019). Putting a New Spin of G-Quadruplex Structure and Binding by Analytical Ultracentrifugation. In Methods in Molecular Biology (Vol. 2035, pp. 87–103). Humana Press Inc. https://doi.org/10.1007/978-1-4939-9666-7_5

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