The genome is organized in 3D topology-associated domains to ensure proper gene transcriptional processes. The chromosome conformation capture (3C) is an affordable method to investigate local chromatin structure and dynamics in cells and tissue. Herein I describe an easy to design and a cost-effective protocol.
CITATION STYLE
Pucéat, M. (2021). Capturing chromosome conformation. In Methods in Molecular Biology (Vol. 2157, pp. 1–7). Humana Press Inc. https://doi.org/10.1007/978-1-0716-0664-3_1
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