Synthesis, Characterization and Biological Activity Studies of Cadmium (II) Complex Derived from Azo Ligand 2-[2\-(5-Bromo Thiazolyl) Azo]-5-Dimethyl Amino Benzoic Acid

Abstract

This study focuses on the synthesis of the 2-[2\-(5-bromo thiazolyl) azo]-5-di-methyl amino benzoic acid (5-BrTAMB) and Cd(II) coordinate complex. Diazotization by 2-amino-5-bromo thiazole and mixation by an alkaline alcohol solution of the 3-dimethyl amino benzoic acid. Various analytical techniques, including 1H-NMR, mass spectral, FT-IR spectra, UV-Vis, elemental analysis (C.H.N.S), measurement of electrical conductivity, magnetic susceptibility, TGA, XRD data and SEM spectra support azo ligand structures and their metal complex. The ligand is the trident N, N, O donor and forms the ML2 [metal-ligand] stoichiometry complex. Cd(II)-complex is found to have exhibited octahedral geometry. The ligand and its metal complex were screened against A. Niger for their antifungal activity and antibacterial activity against S. Aurores and E. Coli.