Mouse Genetics and Breeding

Abstract

The laboratory mouse (Mus musculus) has been employed in biomedical research for its amenability to genetic modification. The genetic modifications have enabled the development of new mouse strains for studying diverse diseases. This chapter will provide information on mouse genetics, their nomenclature, and different strategies of breeding. This chapter will also describe the genetic monitoring program and quality control program associated with it. For ease of learning, we have classified the chapter into four broad categories—selection aids, selection methods, mating aids, and mating methods to facilitate a deeper understanding of mouse genetics and breeding.