Sensory testing might not be perfect - but it is the best biomarker for pain phenotypes we have right now

Abstract

Currently available treatments for neuropathic pain fail in roughly half of the patients - and it is impossible to predict which treatments will help patients. Stratification of neuropathic pain patients is needed, and sensory profiling has so far been the most promising approach: it has been shown to be responsive to treatment, linked to potential mechanisms, and, most importantly, predictive of treatment success. Despite a number of limitations, it is the currently most promising stratification tool and should be refined rather than disregarded.