Antiandrogens

Abstract

In 1986, two reports suggested that hidradenitis suppurativa (HS) responds to antiandrogen therapy [9, 13]. They supported the hypothesis that HS is an androgen-dependent disease. In fact, no further work exists favouring this hypothesis. Furthermore, clinical and biological investigations are really needed to elucidate the possible participation of androgens and the possibility of hyperandrogenism in HS (see Chap. 12, Endocrinology). What a so-called response to antiandrogens in HS means, and the evidence for this is really only poorly suggested, and must be discussed in terms of antiandrogen therapy.