Sulodexide in venous disease

58Citations
Citations of this article
64Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Summary: Sulodexide is a glycosaminoglycan extracted from porcine intestinal mucosa. The purpose of this review is to discuss sulodexide's complex pharmacological profile and its clinical applications for venous disease. Sulodexide has wide-ranging biological effects on the vascular system, including antithrombotic, profibrinolytic, anti-inflammatory, endothelial protective and vasoregulatory effects. Sulodexide has emerged as a potential therapeutic option for the management of chronic venous insufficiency, including venous ulceration, and the prevention of recurrent venous thromboembolism, with a low rate of major bleeding complications. Sulodexide's pleiotropic vascular effects may facilitate the management of common venous disorders.

References Powered by Scopus

Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians evidence-based clinical practice guidelines (8th edition)

1939Citations
N/AReaders
Get full text

The endothelial glycocalyx: Composition, functions, and visualization

1527Citations
N/AReaders
Get full text

The care of patients with varicose veins and associated chronic venous diseases: Clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum

1202Citations
N/AReaders
Get full text

Cited by Powered by Scopus

Why venous leg ulcers have difficulty healing: Overview on pathophysiology, clinical consequences, and treatment

181Citations
N/AReaders
Get full text

Endothelial Injury and Glycocalyx Degradation in Critically Ill Coronavirus Disease 2019 Patients: Implications for Microvascular Platelet Aggregation

92Citations
N/AReaders
Get full text

Global guidelines trends and controversies in lower limb venous and lymphatic disease: Narrative literature revision and experts’ opinions following the vWINter international meeting in Phlebology, Lymphology & Aesthetics, 23–25 January 2019

52Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Carroll, B. J., Piazza, G., & Goldhaber, S. Z. (2019, January 1). Sulodexide in venous disease. Journal of Thrombosis and Haemostasis. Blackwell Publishing Ltd. https://doi.org/10.1111/jth.14324

Readers over time

‘18‘19‘20‘21‘22‘23‘24‘2505101520

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 12

60%

Researcher 4

20%

Professor / Associate Prof. 3

15%

Lecturer / Post doc 1

5%

Readers' Discipline

Tooltip

Medicine and Dentistry 18

75%

Nursing and Health Professions 4

17%

Pharmacology, Toxicology and Pharmaceut... 1

4%

Chemistry 1

4%

Article Metrics

Tooltip
Social Media
Shares, Likes & Comments: 43

Save time finding and organizing research with Mendeley

Sign up for free
0