Understanding differential isoform expression is critical to mechanistically illuminate the biology underlying both normal development and disease states. High-throughput expression profiling analysis of splice variants has thus far been limited by sample requirements and an appropriate platform for quantitation and analysis. Here we describe Affymetrix GeneChip Human Transcriptome Array 2.0, which is employed for comprehensive examination of all known transcript isoforms.
CITATION STYLE
DeVaux, R. S., Kuentzel, M., Herschkowitz, J., & Chittur, S. V. (2017). Determination of alternate splicing events using transcriptome arrays. In Methods in Molecular Biology (Vol. 1507, pp. 245–259). Humana Press Inc. https://doi.org/10.1007/978-1-4939-6518-2_18
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