This case discusses increased clearance of the antiepileptic drug valproic acid in patients with traumatic brain injury during administration of total parenteral nutrition, resulting in subtherapeutic valproic acid levels.
CITATION STYLE
Wittwer, E. D., Nicholson, W. T., & Sprung, J. (2015). TPN (II): A traumatic case of increased metabolism: TPN, valproic acid. In A Case Approach to Perioperative Drug-Drug Interactions (pp. 895–898). Springer New York. https://doi.org/10.1007/978-1-4614-7495-1_201
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