Multi frequency, multi channel, differential impedance analyzer for rapid assays

Abstract

We have developed a multi-channel, multi-sine, differential Impedance Spectrometer as a low cost, fast instrument to monitor the impedance of electrode/specimen interface, at low frequencies (1 - 200 Hz), for assessment of the fast events (down to few seconds/measurement) involved in biosensing. Emphasis will be given to presenting the command and control software of the Multi-Sine Impedance Spectrometer, developed in LabVIEW, with Fourier Transform Core and options for application and analysis of multi-sine and/or single sine waveforms. Using Fourier Transform algorithm and Inverse Fourier Transform, a whole spectrum (1-200 Hz) can be recorded in seconds. The command and control software of the Multi-Sine Impedance Spectrometer enables as well the successive application and analysis of up to 8 sinusoidal waves with different frequencies rendering compatibility with previously developed set-ups and measurement protocols for biosensor assessment. © Springer-Verlag 2007.