Hubungan Kadar Ft4 Dengan Kejadian Tirotoksikosis berdasarkan Penilaian Indeks New Castle Padawanita Dewasa di Daerah Ekses Yodium

  • Rusda H
  • Oenzil F
  • Alioes Y
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Abstract

AbstrakTirotoksikosis merupakan manifestasi klinis yang terjadi akibat peningkatan kadar hormon tiroid dalam darah. Kelebihan yodium merupakan salah satu penyebab terjadinya tirotoksikosis. Ini ditandai dengan hasil pemeriksaan kadar Ekskresi Yodium Urin (EYU) > 199 μg/L. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan kadar FT4 dengan kejadian tirotoksikosis berdasarkan penilaian indeks New Castle pada wanita dewasa di daerah ekses yodium. Metode: Penelitian dilakukan dengan menganalisis data yang dikumpulkan secara Cross Sectional Study terhadap 37 wanita dewasa menggunakan metoda total sampling di Nagari Koto Salak, Kecamatan Koto Salak Kabupaten Dharmasraya yang merupakan daerah ekses yodium (median EYU 323,5 μg/L). Pengumpulan data dilakukan dengan wawancara menggunakan penilaian Indeks New Castle dan pengambilan darah untuk dilakukan pemeriksaan kadar FT4 dalam serum. Hasil: Analisis univariat didapatkan jumlah penduduk wanita dewasa dengan kadar FT4 meningkat sebanyak 14 persen dan nilai rata-rata 1,71 ng/dl. Penilaian indeks New Castle dalam kategori doubtful 16 persen dan tidak ditemukan penduduk yang termasuk dalam kategori toxic. Berdasarkan hasil uji statistik Chi-square, didapatkan p value=1. Kesimpulan: Tidak terdapat hubungan yang bermakna antara kadar FT4 dalam serum dengan kejadian tirotoksikosis pada wanita dewasa di derah ekses yodium. Saran: Perlu dilakukan penyuluhan mengenai asupan yodium kepada masyarakat dan diharapkan penelitian ini dapat menjadi masukan kepada pemerintah dalam mengambil kebijakan terhadap pemberian kapsul yodium serta melakukan kontrol kadar EYU secara teratur dan berkala.Kata kunci: FT4, tirotoksikosis, indeks New Castle, wanita, ekses yodium, tiroidAbstractThyrotoxicosis is a clinical manifestation that occurs due to elevated levels of thyroid hormones in the blood. Iodine excess is one of the causes of thyrotoxicosis. This is indicated by the results of urine iodine excretion levels (EYU) > 199 μg/L. Objective: This study aimed to determine the association FT4 levels with thyrotoxicosis incidence based on New Castle index assessment of adult women in iodine excess area.Method: The study was conducted data analysis which collected with Cross Sectional Study against 37 adult females by using total sampling methods in Koto Salak, Dharmasraya regency which is the iodine excess area (median EYU 323,5 μg/L). Data were collected by using interview New Castle Index assessments and blood sampling for examination FT4 levels in blood serum.Result: Univariate analysis of adult women population is 14 percent in increase category of FT4 levels and 1,71 ng/dl of the average value. New Castle index assessment 16 percent in doubtful category and none included in the toxic category. Based on Chi-Square statistics test, showed p value=1.Conclution: There was no significant association between FT4 levels in blood serum with thyrotoxicosis incidence of adult women in iodine excess area.Suggestion: Therefore, it should be informed to the community about iodine intake and this research is hoped can be input for the government policy towards iodine suplementation and control EYU levels regularly and periodically.Keywords: FT4, thyrotoxicosis, New Castle index, women, iodine excess, thyroid

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APA

Rusda, H., Oenzil, F., & Alioes, Y. (2013). Hubungan Kadar Ft4 Dengan Kejadian Tirotoksikosis berdasarkan Penilaian Indeks New Castle Padawanita Dewasa di Daerah Ekses Yodium. Jurnal Kesehatan Andalas, 2(2), 85. https://doi.org/10.25077/jka.v2i2.126

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