Bilateral Atypical Femur Fracture in a Patient Under Bisphosphonate Treatment

Abstract

Osteoporosis is a systemic skeletal disease that affects most of the elderly people. Bisphosphonate is an effective anti-resorptive drug widely used for the prevention and treatment of osteoporosis. However, recent evidence has linked longterm bisphosphonate use with an atypical fracture. We report a case of a 79-year-old woman who had been on bisphosphonate treatment for eight years and presented with bilateral femur diaphyseal fractures occurring within an interval of a few months. The physicians must consider the possibility of atypical fractures with the fresh onset of groin or mid-thigh pain in patients who have been on bisphosphonate therapy, particularly for more than five years.