Crosscurrents in HIV-1 evolution

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Abstract

Substitutions in CD8+ T cell epitopes in viral proteins can alter the complex interaction between viruses and host immunity. Reduced viral fitness and recognition of altered and subdominant epitopes are possible outcomes. © 2006 Nature Publishing Group.

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Blankson, J. N., Bailey, J. R., & Siliciano, R. F. (2006, February). Crosscurrents in HIV-1 evolution. Nature Immunology. https://doi.org/10.1038/ni0206-121

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