Response to Comment on "Multiple repressive mechanisms in the hippocampus during memory formation

4Citations
Citations of this article
8Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Mathew et al. propose that many candidate genes identified in our study may reflect the events in the choroid plexus (ChP) potentially included in hippocampal samples. We reanalyze our data and find that the ChP inclusion is unlikely to affect our major conclusions regarding the basal suppression of translational machinery or the early translational repression (at 5 to 10 minutes). As Mathew et al. examined for a subset of genes at 4 hours, we agree that the late suppression may partly reflect the events in the ChP. Although the precise contribution of anatomical sources remains to be clarified, our behavioral analyses indicate that the late-phase suppression of these genes may contribute to memory formation.

Cite

CITATION STYLE

APA

Cho, J., Yu, N. K., Kim, V. N., & Kaang, B. K. (2016, July 29). Response to Comment on "Multiple repressive mechanisms in the hippocampus during memory formation. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aaf2081

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free