Multidrug resistance is often associated with the (over)expression of drug efflux transporters of the ATP-binding cassette (ABC) protein family. This minireview discusses the role of one selected ABC-transporter family member, the breast cancer resistance protein (BCRP/ABCG2), in the (pre)clinical efficacy of novel experimental anticancer drugs, in particular tyrosine kinase inhibitors. © 2008 Cancer Research UK.
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CITATION STYLE
Lemos, C., Jansen, G., & Peters, G. J. (2008, March 11). Drug transporters: Recent advances concerning BCRP and tyrosine kinase inhibitors. British Journal of Cancer. https://doi.org/10.1038/sj.bjc.6604213