Wounds: Biology, pathology, and management

Abstract

Wound healing is an orchestrated biological process initiated by tissue injury and culminating in restoration of tissue integrity. The end result of the repair process is fibrosis and scar in all organ systems except bone and except for specialized conditions of liver injury. Because surgeons induce tissue injury, a thorough understanding of the wound repair process is fundamental to the practice of surgery; thus, surgeons and wound repair have enjoyed a close relationship from the beginning of surgery. © 2008 Springer New York.