Finding the missing piece of the puzzle: How NMCPs fit into the plant nuclear lamina

Abstract

The composition of the plant nuclear lamina has long been of interest; while its overall network-like structure is similar to that of other eukaryotes, homologues of the key building blocks-lamins-Are not present in plants. Although plant-specific lamin-like proteins have been characterized, it has remained unknown whether these are indeed present in the plant lamina. Using superresolution microscopy, Masuda et al. (2021) have now solved this puzzle. They show beautifully how the wellstudied Nuclear Matrix Constituent Protein 1 (NMCP1) and NMCP2 form filaments and bundles and are present in a filamentous network at the nuclear periphery-The plant nuclear lamina.