SPECT/PET findings in lewy body dementia

Abstract

Dementia with Lewy bodies (DLB) is the second most common form of dementia. However, it can be diffi cult to diagnose as it shares common features with both Alzheimer’s disease (AD) and Parkinson’s disease (PD). Accurate differentiation from other types of dementia as well as early detection are essential to inform management and treatment. Clinical diagnosis of DLB can be diffi cult, with up to 50 % of cases being misdiagnosed. The use of biomarkers, particularly imaging, has greatly contributed to the accurate diagnosis of DLB. This chapter will give an overview of the contribution of imaging to the diagnosis of DLB and the better understanding of the underlying pathology.