3d-Lectin Database

Abstract

Because of their ubiquitous functions in deciphering the structural information encoded in glycoconjugates at the cell surface, lectins have been the focus of many structural investigations. The 3D-lectin database aims at classifying threedimensional structural features of lectins of all origins. Information about protein fold, oligomerization state, and binding site is also provided. Links to related websites provide bibliographic data as well as information about taxonomy and specificity. Most of the entries correspond to complexes involving biologically important glycans. Related databases of the Glyco3D web portal are directly searchable for each glycan sequence. The present article provides a general description of 3D-lectin database together with examples of data mining.