Keeping viruses in Chk: DNA damage signaling puts the brakes on transformation

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Abstract

Oncogenic viruses infect many cells but rarely lead to tumorigenesis. In this issue of Cell Host & Microbe, Nikitin et al. describe how a protective DNA damage response acts to suppress transformation in the majority of cells latently infected with Epstein-Barr virus (EBV). © 2010 Elsevier Inc.

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Lilley, C. E., & Weitzman, M. D. (2010, December 16). Keeping viruses in Chk: DNA damage signaling puts the brakes on transformation. Cell Host and Microbe. Cell Press. https://doi.org/10.1016/j.chom.2010.11.010

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