Inflammasomes are molecular complexes that initiate innate immune response. They are mainly expressed by immune cells; however, molecular manipulations in these cells remain very difficult. Here, we describe a simple protocol to overexpress and activate functional NRLP3 inflammasomes in HEK293 cells.
CITATION STYLE
Compan, V., & López-Castejón, G. (2016). Functional reconstruction of NLRs in HEK293 cells. In Methods in Molecular Biology (Vol. 1417, pp. 217–221). Humana Press Inc. https://doi.org/10.1007/978-1-4939-3566-6_15
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