Stroke

Abstract

This book chapter aims to discuss the methodology and design of the 100 most highly cited clinical trials in Stroke. We analyzed the main topics of stroke clinical trials aiming to provide insights and valuable information that may improve the development of future trials. We systematically reviewed the 100 most highly cited clinical trials in stroke between the years 2010 and 2015 using the web engine “Web of Science.” A systematic analysis of the 100 most cited clinical trials in stroke based on the CONSORT criteria is discussed; in addition, a summary of all the topics regarding the design of a trial in stroke is provided.