Latent herpes simplex virus type 1 DNA contains two copies of the virion DNA joint region

  • Rock D
  • Fraser N
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Abstract

Southern blot analysis of latent herpes simplex virus DNA detected in mouse brain and digested with a restriction enzyme revealed two copies of the virion DNA joint fragment. Thus, the absence of free ends noted previously in latent herpes simplex virus type 1 DNA is due to joining of the termini.

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Rock, D. L., & Fraser, N. W. (1985). Latent herpes simplex virus type 1 DNA contains two copies of the virion DNA joint region. Journal of Virology, 55(3), 849–852. https://doi.org/10.1128/jvi.55.3.849-852.1985

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