Photodynamic therapy for benign lesions

Abstract

Photodynamic therapy (PDT) is an effective treatment for non-melanoma skin cancers and their precursors. PDT has also been used as an off-label alternative treatment for benign skin diseases/conditions. Among them acne and photoaging attract most considerable attention. PDT may also be of some benefit for the treatment of fungal infections, viral warts, cutaneous leishmaniasis, leg ulcers, lichenoid dermatoses, and some granulomatous skin disorders. However, firm conclusions cannot be made because of the small total number of patients assessed and the short follow-up period.